Androgen receptor

Scientific explanation

AR is a nuclear factor required for most prostate adenocarcinoma growth. Resistance can occur through AR amplification, splice variants, or lineage plasticity.

Cancers where relevant

Prostate cancer Androgen-sensitive prostate cancer Castration-resistant prostate cancer

Compounds that intersect this pathway

This oncology atlas is educational. Pathway maps, adjunctive strategies, and compound listings describe mechanistic relevance. They do not establish clinical efficacy, do not recommend treatment, and are not a substitute for oncology care. Evidence tiers are not equivalent.